Jumpstart Your Panel Design with OMIP's
By David Stegemeier
Designing a multicolor fluorescent panel can take months to develop and optimize. Fortunately, Optimized Multicolor Immunofluorescence Panels (OMIPs) have greatly reduced this process. Now, researchers can recreate any published OMIP on FluoroFinder and easily edit them as necessary.
OMIPs are a series of peer-reviewed and optimized multicolor panels for flow cytometry and fluorescence microscopy published in Cytometry Part A. Intended to alleviate development time for researchers while acknowledging the developers’ work, OMIPs provide a useful starting point for the creation of similar panels.
“When we first introduced the OMIP publication format we had also envisioned a searchable online tool that would link to relevant OMIPs according to a selected cell type, markers, or species. FluoroFinder is working to integrate OMIPs into its online panel building platform, which promises to make alteration of previously optimized panels even easier”, said flow cytometry consultant and original OMIP developer Yolanda Mahnke, PhD. “This will not eliminate the need to thoroughly test any panel before its application in your studies, but it will shorten the process.”
Adapt a Published OMIP with your FluoroFinder Account
As of October 2016, 37 OMIPs have been approved and published. These panels focus almost exclusively on blood and immunology research on leukocyte populations from human, mouse or monkey samples. Researchers who are designing similar experiments are encouraged to review the OMIP list and use these pre-validated panels as a resource for their own panel development.
Unsure how to adapt an OMIP panel to your experiment? Contact our expert panel concierge service for customized consulting solutions! Consulting is available at hourly rates or on a per project basis.
Publish Your Panel as the Next OMIP
Have you developed a multicolor panel that you feel would be beneficial to share with others studying in your field? Submit your OMIP proposal to Cytometry Part A for recognition in the publication. Follow the guidelines laid out in the introductory OMIP series article.