So many new fluorophores have been released in recent years, it can be hard to keep track of their similarities or novelty. Sometimes, a company will create a new brand name for a fluorescent chemistry that is already commonly used, which can make sifting through the...
Single-cell analysis techniques such as fluorescence-activated cell sorting (FACS) and single-cell DNA and RNA sequencing have broadened researchers’ understanding of cell biology in health and disease by enabling the study of rare cell types and phenotype variations...
Standardization may not be the most exciting topic in biomedical research, but in an era where we lament the lack of reproducibility and distribute blame to reagents, sample prep, and general technical know-how, standardization is something every researcher should...
Two-dimensional (2D) cell cultures represent a cornerstone of scientific research due to their relative simplicity and the establishment of standard techniques over time. In recent years though, 3D cell culture models have risen in popularity for the more...
What is Spectral Spillover? In flow cytometry, spectral spillover occurs when the emission of one fluorophore overlaps the optimal detection channel of a different fluorophore. Spillover is a concern in flow cytometry, as it can make fluorescent signatures difficult...
