Back before spectral cytometry, flow cytometers were composed of optical configurations with individual photomultiplier tubes (PMTs) or avalanche photodiodes (APDs) behind filters centered at the peak emission of different fluorophores. Many might call these...
Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based light microscopy, even when employing phase or other contrast-enhancing...
Fluorescent detection is one of the most powerful tools available to researchers. Not only does it offer the advantages of high sensitivity, simple operation, and the capacity for multiplexing, but it also allows for capturing dynamic biological processes in...
