Fluorescence-activated cell sorting (FACS) is an advanced form of flow cytometry that allows researchers to isolate specific cell types from a heterogeneous sample. This article explains the basic principles of FACS and describes some common research applications. It...
Cover Image: Imaging of the whole-brain vasculatures at sub-cellular resolution. Brains of adult Tie2-Cre;tTAflox;tetO-H2BGFP (TTH) mice were cleared using the PEGASOS method and imaged with a tiling light-sheet microscope. g An X-Z optical slice acquired at the...
When selecting reagents for flow cytometry, fluorescently-labeled antibodies are likely the first products that come to mind. However, supplementary reagents are also important and it pays to investigate what’s on offer. This article looks at some of the different...
Guest Authored By: Vera Tang, Ph.D. Interest in the study of extracellular vesicles has increased exponentially over the past two decades due to the important role they play in inter-cellular communication, as biomarkers of disease, and vehicles for drug delivery....